Adverse Events Clinical Questions Addressed

1. Which AEs are elevated in treatment vs. control? Which AE could be a safety signal?

EG Most Frequent AE	EG P-risk Plot	EG Hazard Ratios
Click here for Most Frequent AE Data	Click here for P-risk Plot Data	Click here for Hazard Ratios Data
Comment on Most Frequent AE	Comment on P-risk Plot Data	Comment on Hazard Ratios

2. Which AE could be a safety signal?

EG Most Frequent AE	EG P-risk Plot
Click here for Most Frequent AE Data	Click here for P-risk Plot Data
Comment on Most Frequent AE	Comment on P-risk Plot Data

3. Is there a difference in the time to the first event across treatment groups?

EG Time to AE Occurrence
Click here for Time to AE Occurrence Data
Comment on Time to AE Occurrence

4. What are the trends of time to the first event among different AEs?

EG Time to AE Occurrence
Click here for Time to AE Occurrence Data
Comment on Time to AE Occurrence

5. Which AEs are elevated in patient subgroups?

EG Hazard Ratios
Click here for Hazard Ratios Data
Comment on Hazard Ratios

6. What are the risk factors for an AE?

EG Hazard Ratios
Click here for Hazard Ratios Data
Comment on Hazard Ratios