Web Services for Tasks Associated with Statistical Analyses

These resources go beyond statistical calculators, but do not require computational skills.

MuStat/ustat

u-Statistics for multivariate ordinal data (grid powered Web server, muNews RSS feed, discuss)
Knut M. Wittkowski, The Rockefeller University, Email;
maintained by: Tingting Song, Email
Reference: Nonparametric methods for molecular biology (Wittkowski 2010)
(based on muStat package for multivariate ordinal data, see R Packages)

• scoring complex phenotypes (including recurrent, graded, and censored adverse events with varying attribution (Morales (2008))
• screening microarrays for gene expression profiles (sets of collaborating genes)
• screening whole genome scans for epistasis between multipoint ranges (diplotypes)
• sorting hierarchical genotype/expression/phenotype factor structures by information content
• developing metrics for biostatistical and epidemiological collaborations (Rubio 2011)

WISDOM

Web-based Interactive Study Design, Organization, and Management (discuss)
Knut M. Wittkowski, The Rockefeller University, Email
References: Roadmap integration, Progress
WISDOM provides a GUI and a layered study meta data ontology for:

• importing study meta data from previous studies and standardized outcomes ontologies,
• automatically creating an Oracle data base
• exporting CRF definitions (data dictionaries) into REDCap (Vanderbilt) and Epi Info™ (CDC)
• copying and pasting data between spreadsheets (MS Excel, OO Calc ...) and statistical programs (SPSS, SAS ...) and a Web-accessible and secure ORACLE data base for sharing with collaborators.
• importing data from various sources (in progress)
• assisting analyses with \xB5Stat , R, SAS, ... (in progress)
• setting up interim analyses to report study progress and emerging risks (planned)
• automatically producing analyses for primary objectives (planned)
• conducting bootstrapped power calculations (planned)
• facilitating data sharing by adding study design information (in progress).

Attachments

• Slideshow: Integration of Online Resources: WISDOM / REDCap. BERD Online Resources and Education Meeting, 2009-06-09
• Handout: Responding to New Challenges: Statistics in Clinical and Translational Science . JSM, Denver, CO, 2008-08-04
• Handout: An Ontology for Biostatistics. CTSA BERD Workgroup meeting, 2007-11-14
• Slideshow: Research Design and Biostatistics Support at the RU CCTS. 2007-05-11
• Concept Paper: Towards Novel Nonparametric Statistical Methods and Bioinformatics Tools for Clinical and Translational Sciences. NIH Roadmap meeting, 2005-05-23

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Topic revision: 09 May 2013, MaryBanach

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