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Topic revision: 30 Mar 2012, MaryBanach
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| Image | %LIGHTBOX{ image="misspersp.jpg" thumbnail="tn_misspersp.jpg" caption="Sensitvity Analysis" }% Click to enlarge image. |
| Title | Sensitivity Analysis of Missing Data |
| Graph_Subgroup | General Principles |
| Code Added | Yes |
| Description | X and Y depict the percentage of the missing data which is imputed as responder. Z depicts the resulting chi-square statistic, two-sided alpha = 0.05 significance level would be 3.84 (cyan). |
| Contributor/Email | Mat Soukup (email: Mat.Soukup@fda.hhs.gov) |
| Background | Binary outcome is defined as a two grade improvement from baseline value. The data set is from a randomly generated data set located on the OB network drive. Impact |
| Special Considerations | |
| Date | Original |
| Original Date | 2007 |
| Modified Date | |
| Use/Suitability | Publication |
| Software Program | R |
| Software | |
| R-Code - Attachment | R-script: Sensitivity Analysis of Missing Data |
| R-Code | dat <- read.csv('//cdsnas/oebdbdms/Graphics/Datasets/CleanTrial.csv')<br /> eot <- subset(dat, visit%in%6)<br />eot$binep <- ifelse(base$catvar-eot$catvar >= 2, 1, 0) # Reduce size of data for easier calculation ii <- sample(1:1500, 500, replace=FALSE)<br />eot2 <- eot[-ii,]<br /> # Force some of the data to be missing (10% of data) set.seed(77) ww <- sample(1:1000, 100, replace=FALSE)<br />eot2$binep[ww] <- NA<br />ind <- eot2$binep[eot2$trtf%in%'Active']<br />ctl <- eot2$binep[eot2$trtf%in%'Placebo']<br /> source("//cdsnas/oebdbdms/Graphics/Scripts/MissSens.txt") #png('C:/Research/Graphics/Graphs4Display/webpages/classes/pages/images/misspersp.png', # width=500, height=500) pp <- miss.plot(ind, # Trt. arm with missing<br /> ctl, # Control arm with missing theta=305, # See option theta in persp phi=25, # See option phi in persp nticks=5, # See option nticks in persp zpch.cex=1, # Size of the square plotted on the z-axis plane=FALSE, border='black', ltheta=305, lphi=25, main="") #dev.off() |
| SAS-Code - Attachment | |
| SAS-Code | |
| Stata-Code - Attachment | |
| Stata-Code | |
| Other Code - Attachment | |
| Other Code | |
| Keywords | sensitivity analysis, missing data, chi-square statistic |
| OPTIONAL FIELDS | |
| References | |
| Datasets | |
| Data | |
| Attached Data | |
| CATEGORIZATIONS | |
| Classification-Evaluation | Efficacy |
| Classification-Graph Type | Perspective Plot |
| Graph_Type | Perspective Plot |
| Variable Relationship | Categorical versus Categorical |
| Data Types | Categorical |
| Special Cases | |
| Disclaimer | The views expressed within CTSpedia are those of the author and must not be taken to represent policy or guidance on the behalf of any organization or institution with which the author is affiliated. |
| Permission | Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF ERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT OLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. |
| Reference Image |  |
Topic revision: 30 Mar 2012, MaryBanach
Copyright © by the contributing authors. All material on this collaboration platform is the property of the contributing authors. Ideas, requests, problems regarding Foswiki? Send feedback